Discover the science behind Niacinamide, a popular cosmetic ingredient known for supporting the skin barrier, managing oil appearance, and promoting a healthy-looking complexion.
Explore the MoleculeNiacinamide, also known as nicotinamide, is a water-soluble form of vitamin B3. It is an essential nutrient that the body needs for optimal health, playing a crucial role in cellular energy production.
Unlike nicotinic acid (another form of vitamin B3), niacinamide typically does not cause skin flushing. In the realm of cosmetic chemistry, it is celebrated for its high tolerability and multi-functional benefits, making it suitable for a wide variety of skin types.
Commonly utilized in modern cosmetic formulations.
Interact with the 3D model below. You can rotate, zoom, and inspect the pyridine-3-carboxamide molecule structure.
IUPAC Name
Pyridine-3-carboxamide
Chemical Formula
C6H6N2O
Molar Mass
122.12 g/mol
PubChem CID
936A multi-tasking ingredient known to support overall skin appearance and texture.
Helps maintain the skin's natural moisture barrier, assisting in retaining hydration and protecting against environmental stressors.
Assists in visibly balancing the appearance of oil on the skin, helping to reduce excess shine and maintain a clearer-looking complexion.
By managing surface oil and debris, niacinamide can help visibly minimize the look of enlarged pores, promoting smoother-looking skin.
Helps to visibly improve the look of uneven skin tone and dark spots, contributing to a more radiant and brighter overall complexion.
Found in products formulated for twice-daily use, morning and night.
Often utilized in cosmetics between 2% to 5%. Concentrations of 10% or higher might be irritating for sensitive skin.
Most clinical studies show efficacy between 2% to 5%. Concentrations of 10% or higher may cause irritation in sensitive skin.
Plays well with almost all other active ingredients, including Retinol, Peptides, and Hyaluronic Acid.
Yes. The old myth that you cannot mix Niacinamide with Vitamin C (Ascorbic Acid) is based on outdated research from the 1960s using un-stabilized forms of the ingredients at extreme temperatures. In modern cosmetic formulations, layering them together is completely safe and actually provides a synergistic antioxidant and brightening effect.
The information provided on this website is for educational and informational purposes only and does not constitute medical advice. Skincare needs vary greatly from person to person, and what works for one may not be suitable for another. Always consult with a board-certified dermatologist or qualified healthcare professional before incorporating new active ingredients into your routine, especially if you have sensitive skin or pre-existing skin conditions.